STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ganRTranscriptional regulator (LacI family); Negatively regulates expression of ganA. (330 aa)    
Predicted Functional Partners:
cycB
Cyclodextrin-binding lipoprotein; Binding protein for cyclodextrin; involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha, beta and gamma; Belongs to the bacterial solute-binding protein 1 family.
 
  
 0.850
licR
Transcriptional activator of the lichenan operon; Positive regulator of the licABCH operon; Belongs to the transcriptional antiterminator BglG family.
      
 0.845
ganQ
Arabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane.
  
  
 0.841
ganP
Arabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane.
  
  
 0.819
ccpB
Transcriptional repressor of carbon supply (LacI family); Transcriptional regulator involved in catabolite repression of several operons.
  
  
 0.807
ganB
Secreted arabinogalactan oligomer endo-hydrolase; Hydrolyzes the beta-1,4-galactan linkages of arabinogalactan type I, a pectic substance found in plants such as soybeans.
 
  
 0.786
yvfI
Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis.
 
 
 0.780
araR
Transcriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter.
  
  
 0.770
ganA
Arabinogalactan type I oligomer exo-hydrolase (beta-galactosidase, lactase); Hydrolyzes oligosaccharides released by the endo-1,4-beta- galactosidase GalA from arabinogalactan type I, a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source. Maximal activity with o-nitrophenyl-beta-D-galactopyranoside (ONPG) and p-nitrophenyl-beta-D-galactopyranoside (PNPG) as substrates, trace activity with p-nitrophenyl-alpha-L-arabinopyranoside and o- nitrophenyl-beta-D-fucopyranoside as substrates, but no activity with p-nitrophenyl-alpha-D-galactopyranoside, p-nitrophenyl [...]
 
   
 0.763
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.763
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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