node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frlR | gntR | BSU32560 | BSU40050 | FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. | 0.737 |
frlR | nagR | BSU32560 | BSU35030 | FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Transcriptional regulator (GntR family); Main transcriptional repressor of genes involved in N- acetylglucosamine (GlcNAc) transport and utilization. Represses the expression of the nagAB and nagP operons by binding directly within their upstream regions. Binds to the DNA consensus sequence 5'-ATTGGTATAGACAACT-3'. Also acts as a weak repressor of mapB expression. | 0.452 |
frlR | yvfI | BSU32560 | BSU34180 | FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.580 |
ganR | yvfI | BSU34170 | BSU34180 | Transcriptional regulator (LacI family); Negatively regulates expression of ganA. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.729 |
gmuR | yvfI | BSU05850 | BSU34180 | Transcriptional regulator (GntR family); Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.550 |
gntR | frlR | BSU40050 | BSU32560 | Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. | FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | 0.737 |
gntR | nagR | BSU40050 | BSU35030 | Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. | Transcriptional regulator (GntR family); Main transcriptional repressor of genes involved in N- acetylglucosamine (GlcNAc) transport and utilization. Represses the expression of the nagAB and nagP operons by binding directly within their upstream regions. Binds to the DNA consensus sequence 5'-ATTGGTATAGACAACT-3'. Also acts as a weak repressor of mapB expression. | 0.918 |
gntR | ybgA | BSU40050 | BSU02370 | Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. | Putative transcriptional regulator (GntR family); Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region. | 0.734 |
gntR | yvfI | BSU40050 | BSU34180 | Transcriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.757 |
lutA | lutB | BSU34050 | BSU34040 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutA | lutC | BSU34050 | BSU34030 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutA | yvfH | BSU34050 | BSU34190 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.726 |
lutA | yvfI | BSU34050 | BSU34180 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.677 |
lutB | lutA | BSU34040 | BSU34050 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutB | lutC | BSU34040 | BSU34030 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutB | yvfH | BSU34040 | BSU34190 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.857 |
lutB | yvfI | BSU34040 | BSU34180 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.777 |
lutC | lutA | BSU34030 | BSU34050 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutC | lutB | BSU34030 | BSU34040 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
lutC | yvfH | BSU34030 | BSU34190 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.729 |