| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fni | yvfH | BSU22870 | BSU34190 | Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.722 |
| ldh | nasD | BSU03050 | BSU03300 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. | 0.428 |
| ldh | yvfH | BSU03050 | BSU34190 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.790 |
| lutA | lutB | BSU34050 | BSU34040 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutA | lutC | BSU34050 | BSU34030 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutA | yvfH | BSU34050 | BSU34190 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.669 |
| lutA | yvfI | BSU34050 | BSU34180 | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.728 |
| lutB | lutA | BSU34040 | BSU34050 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutB | lutC | BSU34040 | BSU34030 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutB | yvfH | BSU34040 | BSU34190 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.757 |
| lutB | yvfI | BSU34040 | BSU34180 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.771 |
| lutC | lutA | BSU34030 | BSU34050 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutC | lutB | BSU34030 | BSU34040 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | 0.999 |
| lutC | yvfH | BSU34030 | BSU34190 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.734 |
| lutC | yvfI | BSU34030 | BSU34180 | Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present. | Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis. | 0.764 |
| nasD | ldh | BSU03300 | BSU03050 | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. | 0.428 |
| nasD | nasE | BSU03300 | BSU03290 | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity). | 0.999 |
| nasD | yvfH | BSU03300 | BSU34190 | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.462 |
| nasE | nasD | BSU03290 | BSU03300 | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity). | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. | 0.999 |
| nasE | yvfH | BSU03290 | BSU34190 | Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity). | Putative lactate permease; Is the principal permease for the uptake of L-lactate in B.subtilis. | 0.450 |
