STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
epsBProtein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family. (227 aa)    
Predicted Functional Partners:
epsA
Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator.
 
 0.999
ywqC
Modulator of YwqD protein tyrosine kinase activity; Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis.
 
 0.998
epsC
Putative UDP-sugar epimerase; Involved in biofilm formation; Belongs to the polysaccharide synthase family.
 
  
 0.985
epsE
Bifunctional flagellar clutch and glycosyltransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family.
 
  
 0.977
ywqE
Protein tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins YwqD, YwqF and Ssb.
  
 0.965
epsL
Putative phosphotransferase involved in extracellular matrix synthesis; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles.
 
  
 0.963
epsD
Putative extracellular matrix biosynthesis enzyme; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  
  
 0.951
epsN
Putative aminotransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles.
  
  
 0.946
epsF
Putative glycosyltransferase involved in extracellular matrix formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
 
  
 0.923
epsO
Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the polysaccharide pyruvyl transferase family.
 
  
 0.915
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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