| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bslA | epsA | BSU31080 | BSU34370 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | 0.974 |
| bslA | epsB | BSU31080 | BSU34360 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family. | 0.482 |
| bslA | epsE | BSU31080 | BSU34330 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Bifunctional flagellar clutch and glycosyltransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family. | 0.742 |
| bslA | epsH | BSU31080 | BSU34300 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Putative glycosyltransferase involved in biofilm formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family. | 0.532 |
| bslA | epsO | BSU31080 | BSU34220 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the polysaccharide pyruvyl transferase family. | 0.557 |
| bslA | sipW | BSU31080 | BSU24630 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family. | 0.936 |
| bslA | slrR | BSU31080 | BSU34380 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Transcriptional regulator of autolysin genes; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation. | 0.788 |
| bslA | tapA | BSU31080 | BSU24640 | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of TasA fibers. | 0.973 |
| epsA | bslA | BSU34370 | BSU31080 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | 0.974 |
| epsA | epsB | BSU34370 | BSU34360 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family. | 0.999 |
| epsA | epsC | BSU34370 | BSU34350 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Putative UDP-sugar epimerase; Involved in biofilm formation; Belongs to the polysaccharide synthase family. | 0.979 |
| epsA | epsE | BSU34370 | BSU34330 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Bifunctional flagellar clutch and glycosyltransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family. | 0.984 |
| epsA | epsH | BSU34370 | BSU34300 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Putative glycosyltransferase involved in biofilm formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family. | 0.978 |
| epsA | epsO | BSU34370 | BSU34220 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the polysaccharide pyruvyl transferase family. | 0.986 |
| epsA | ptkA | BSU34370 | BSU36250 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | 0.979 |
| epsA | sipW | BSU34370 | BSU24630 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family. | 0.997 |
| epsA | slrR | BSU34370 | BSU34380 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Transcriptional regulator of autolysin genes; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation. | 0.973 |
| epsA | tapA | BSU34370 | BSU24640 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of TasA fibers. | 0.995 |
| epsB | bslA | BSU34360 | BSU31080 | Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family. | Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. | 0.482 |
| epsB | epsA | BSU34360 | BSU34370 | Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family. | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | 0.999 |
