Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yvcBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (636 aa)    
Predicted Functional Partners:
yvcA
Putative lipoprotein; Required for complex colony architecture.
  
  
 0.983
yvzA
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.929
yjaU
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.804
hisI
phosphoribosyl-AMP cyclohydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; In the C-terminal section; belongs to the PRA-PH family.
     
 0.669
hisF
Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
  
  
 0.645
ywqI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.635
yukC
Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
  
    0.571
yukD
Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family.
  
    0.518
yxiB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.499
yxiC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.493
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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