node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
codY | sepF | BSU16170 | BSU15390 | Transcriptional regulator, GTP and BCAA-dependent; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase and sporulation. It is a GTP- binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family. | 0.542 |
codY | ywtF | BSU16170 | BSU35840 | Transcriptional regulator, GTP and BCAA-dependent; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase and sporulation. It is a GTP- binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.536 |
pbpD | ywtF | BSU31490 | BSU35840 | Penicillin-binding protein 4; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; In the C-terminal section; belongs to the transpeptidase family. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.574 |
recF | sepF | BSU00040 | BSU15390 | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family. | 0.481 |
recF | ywtF | BSU00040 | BSU35840 | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.529 |
sepF | codY | BSU15390 | BSU16170 | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family. | Transcriptional regulator, GTP and BCAA-dependent; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase and sporulation. It is a GTP- binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. | 0.542 |
sepF | recF | BSU15390 | BSU00040 | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family. | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | 0.481 |
sepF | ywtF | BSU15390 | BSU35840 | Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.512 |
tagF | tagH | BSU35720 | BSU35700 | Teichoic acid poly(glycerol phosphate) polymerase; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length. | Teichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. | 0.993 |
tagF | ywtF | BSU35720 | BSU35840 | Teichoic acid poly(glycerol phosphate) polymerase; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.518 |
tagH | tagF | BSU35700 | BSU35720 | Teichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. | Teichoic acid poly(glycerol phosphate) polymerase; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length. | 0.993 |
tagH | ywtF | BSU35700 | BSU35840 | Teichoic acids export ATP-binding protein TagH; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.526 |
ybfF | ybfG | BSU02190 | BSU02200 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | 0.893 |
ybfF | ycbL | BSU02190 | BSU02550 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Two-component response regulator [YcbM]; Member of the two-component regulatory system YcbM/YcbL. | 0.687 |
ybfF | ywtE | BSU02190 | BSU35850 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative hydrolase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. Also catalyzes the dephosphorylation of phosphorylated 5-6 carbon sugars and monophosphate nucleotides (NMP) in vitro. | 0.682 |
ybfF | ywtF | BSU02190 | BSU35840 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.485 |
ybfG | ybfF | BSU02200 | BSU02190 | Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.893 |
ybfG | ycbL | BSU02200 | BSU02550 | Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Two-component response regulator [YcbM]; Member of the two-component regulatory system YcbM/YcbL. | 0.700 |
ybfG | ywtE | BSU02200 | BSU35850 | Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Putative hydrolase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. Also catalyzes the dephosphorylation of phosphorylated 5-6 carbon sugars and monophosphate nucleotides (NMP) in vitro. | 0.681 |
ybfG | ywtF | BSU02200 | BSU35840 | Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Putative transcriptional regulator; May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG). | 0.549 |