node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
capA | capB | BSU35880 | BSU35900 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | 0.995 |
capA | capC | BSU35880 | BSU35890 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | 0.998 |
capA | capE | BSU35880 | BSU35870 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | Factor required for polyglutamate synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.973 |
capA | pgdS | BSU35880 | BSU35860 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | gamma-DD-glutamyl hydrolase (PGA depolymerase); Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). | 0.882 |
capA | yjqB | BSU35880 | BSU12480 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | Putative PBSX phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the UPF0714 family. | 0.403 |
capA | ymaC | BSU35880 | BSU17270 | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | Conserved hypothetical protein; Evidence 7: Gene remnant; Belongs to the UPF0714 family. | 0.403 |
capB | capA | BSU35900 | BSU35880 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | 0.995 |
capB | capC | BSU35900 | BSU35890 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | 0.999 |
capB | capE | BSU35900 | BSU35870 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Factor required for polyglutamate synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.995 |
capB | divIB | BSU35900 | BSU15240 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Cell-division initiation protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures, maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation. B [...] | 0.812 |
capB | murF | BSU35900 | BSU04570 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.813 |
capB | pgdS | BSU35900 | BSU35860 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | gamma-DD-glutamyl hydrolase (PGA depolymerase); Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). | 0.964 |
capB | yjqB | BSU35900 | BSU12480 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Putative PBSX phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the UPF0714 family. | 0.878 |
capB | ymaC | BSU35900 | BSU17270 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Conserved hypothetical protein; Evidence 7: Gene remnant; Belongs to the UPF0714 family. | 0.877 |
capB | yoqZ | BSU35900 | BSU20460 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0714 family. | 0.839 |
capB | yrpC | BSU35900 | BSU26810 | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.797 |
capC | capA | BSU35890 | BSU35880 | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | Capsular polyglutamate synthetase; Seems to be required for maximum PGA (gamma-polyglutamic acid) production; Belongs to the CapA family. | 0.998 |
capC | capB | BSU35890 | BSU35900 | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | Capsular polyglutamate synthetase (ATP-dependent amide ligase); Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis. | 0.999 |
capC | capE | BSU35890 | BSU35870 | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | Factor required for polyglutamate synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.996 |
capC | pgdS | BSU35890 | BSU35860 | Capsular polyglutamate amide ligase/translocase subunit; Required for PGA (gamma-polyglutamic acid) biosynthesis. | gamma-DD-glutamyl hydrolase (PGA depolymerase); Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). | 0.964 |