node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bscR | ptkA | BSU27170 | BSU36250 | Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon. | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | 0.912 |
bscR | salA | BSU27170 | BSU01540 | Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon. | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.634 |
bscR | ywqC | BSU27170 | BSU36260 | Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon. | Modulator of YwqD protein tyrosine kinase activity; Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis. | 0.431 |
epsA | ptkA | BSU34370 | BSU36250 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | 0.978 |
epsA | ywqC | BSU34370 | BSU36260 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Modulator of YwqD protein tyrosine kinase activity; Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis. | 0.813 |
epsA | ywqE | BSU34370 | BSU36240 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Protein tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins YwqD, YwqF and Ssb. | 0.903 |
ptkA | bscR | BSU36250 | BSU27170 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon. | 0.912 |
ptkA | epsA | BSU36250 | BSU34370 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | 0.978 |
ptkA | salA | BSU36250 | BSU01540 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.857 |
ptkA | tuaD | BSU36250 | BSU35580 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | UDP-glucose 6-dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.861 |
ptkA | yabT | BSU36250 | BSU00660 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.872 |
ptkA | yfkJ | BSU36250 | BSU07880 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Protein-tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance. | 0.914 |
ptkA | ywlE | BSU36250 | BSU36930 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Protein-tyrosine-phosphatase; Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-P; thus, can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B.subtilis. Exhibits almost no activity against pSer, pThr, or pTyr peptides. Appears to play a role in B.subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved i [...] | 0.865 |
ptkA | ywqC | BSU36250 | BSU36260 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Modulator of YwqD protein tyrosine kinase activity; Required for YwqD kinase activity. May bring YwqD and its substrates into contact. Probably involved in the regulation of capsular polysaccharide biosynthesis. | 0.999 |
ptkA | ywqE | BSU36250 | BSU36240 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | Protein tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins YwqD, YwqF and Ssb. | 0.998 |
ptkA | ywqF | BSU36250 | BSU36230 | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.908 |
salA | bscR | BSU01540 | BSU27170 | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon. | 0.634 |
salA | ptkA | BSU01540 | BSU36250 | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Protein tyrosine kinase; May be involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylates in vitro. Phosphorylates and activates in vitro two UDP-glucose dehydrogenases, YwqF and TuaD, as well as the DNA-binding proteins Ssb and SsbB; Belongs to the CpsD/CapB family. | 0.857 |
salA | yabT | BSU01540 | BSU00660 | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.541 |
salA | yfkJ | BSU01540 | BSU07880 | Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Protein-tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance. | 0.479 |