node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddl | ftsW | BSU04560 | BSU14850 | D-alanyl-D-alanine ligase A; Cell wall formation. | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | 0.870 |
ddl | gcaD | BSU04560 | BSU00500 | D-alanyl-D-alanine ligase A; Cell wall formation. | Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belon [...] | 0.611 |
ddl | murAA | BSU04560 | BSU36760 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Essential for cell growth; Belongs to the EPSP synthase family. MurA subfamily. | 0.945 |
ddl | murB | BSU04560 | BSU15230 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.997 |
ddl | murC | BSU04560 | BSU29790 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetyl muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.997 |
ddl | murD | BSU04560 | BSU15200 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.975 |
ddl | murE | BSU04560 | BSU15180 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.951 |
ddl | murF | BSU04560 | BSU04570 | D-alanyl-D-alanine ligase A; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
ddl | murG | BSU04560 | BSU15220 | D-alanyl-D-alanine ligase A; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.958 |
ftsW | ddl | BSU14850 | BSU04560 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | D-alanyl-D-alanine ligase A; Cell wall formation. | 0.870 |
ftsW | murAA | BSU14850 | BSU36760 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Essential for cell growth; Belongs to the EPSP synthase family. MurA subfamily. | 0.922 |
ftsW | murB | BSU14850 | BSU15230 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.754 |
ftsW | murC | BSU14850 | BSU29790 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetyl muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.956 |
ftsW | murD | BSU14850 | BSU15200 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.947 |
ftsW | murE | BSU14850 | BSU15180 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.877 |
ftsW | murF | BSU14850 | BSU04570 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.946 |
ftsW | murG | BSU14850 | BSU15220 | Cell-division protein; Peptidoglycan polymerase that is essential for cell division. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.985 |
gcaD | ddl | BSU00500 | BSU04560 | Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belon [...] | D-alanyl-D-alanine ligase A; Cell wall formation. | 0.611 |
gcaD | mnaA | BSU00500 | BSU35660 | Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belon [...] | UDP-N-acetylmannosamine 2-epimerase; Catalyzes the conversion of UDP-N-acetylglucosamine into UDP- N-acetylmannosamine, a precursor of the teichoic acid linkage unit. | 0.930 |
gcaD | murAA | BSU00500 | BSU36760 | Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belon [...] | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Essential for cell growth; Belongs to the EPSP synthase family. MurA subfamily. | 0.990 |