| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| albA | albD | BSU37370 | BSU37400 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | 0.996 |
| albA | albF | BSU37370 | BSU37420 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | 0.979 |
| albA | argS | BSU37370 | BSU37330 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | arginyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.436 |
| albA | sboA | BSU37370 | BSU37350 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. | 0.963 |
| albA | ywiB | BSU37370 | BSU37340 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.632 |
| albD | albA | BSU37400 | BSU37370 | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | 0.996 |
| albD | albF | BSU37400 | BSU37420 | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | 0.967 |
| albD | sboA | BSU37400 | BSU37350 | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. | 0.821 |
| albD | ywiB | BSU37400 | BSU37340 | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.635 |
| albF | albA | BSU37420 | BSU37370 | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | 0.979 |
| albF | albD | BSU37420 | BSU37400 | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | 0.967 |
| albF | sboA | BSU37420 | BSU37350 | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. | 0.940 |
| albF | ywiB | BSU37420 | BSU37340 | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.585 |
| argS | albA | BSU37330 | BSU37370 | arginyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | 0.436 |
| argS | ywiB | BSU37330 | BSU37340 | arginyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.942 |
| braB | yjcM | BSU29600 | BSU11910 | Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.424 |
| braB | yjcN | BSU29600 | BSU11920 | Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
| braB | yutJ | BSU29600 | BSU32200 | Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. | Putative NADH dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.577 |
| braB | yuzB | BSU29600 | BSU32190 | Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0349 family. | 0.607 |
| braB | ywiB | BSU29600 | BSU37340 | Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.739 |
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