| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| albA | albB | BSU37370 | BSU37380 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | 0.997 |
| albA | albC | BSU37370 | BSU37390 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative transporter involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin; Belongs to the ABC transporter superfamily. | 0.989 |
| albA | albD | BSU37370 | BSU37400 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | 0.996 |
| albA | albE | BSU37370 | BSU37410 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative hydrolase involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. | 0.980 |
| albA | albF | BSU37370 | BSU37420 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | 0.977 |
| albA | albG | BSU37370 | BSU37430 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. | 0.975 |
| albA | csn | BSU37370 | BSU26890 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan. | 0.466 |
| albA | sboA | BSU37370 | BSU37350 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. | 0.981 |
| albA | sboX | BSU37370 | BSU37360 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Putative bacteriocin-like product; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.962 |
| albA | ywiB | BSU37370 | BSU37340 | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.612 |
| albB | albA | BSU37380 | BSU37370 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | 0.997 |
| albB | albC | BSU37380 | BSU37390 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative transporter involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin; Belongs to the ABC transporter superfamily. | 0.991 |
| albB | albD | BSU37380 | BSU37400 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin. | 0.996 |
| albB | albE | BSU37380 | BSU37410 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative hydrolase involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. | 0.973 |
| albB | albF | BSU37380 | BSU37420 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative peptidase involved in subtilosin production; Required for production of the bacteriocin subtilosin. Could catalyze some step in the processing of presubtilosin. | 0.965 |
| albB | albG | BSU37380 | BSU37430 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative integral inner membrane protein involved in subtilosin production and immunity; Involved in the production of the bacteriocin subtilosin. | 0.977 |
| albB | csn | BSU37380 | BSU26890 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan. | 0.485 |
| albB | sboA | BSU37380 | BSU37350 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Subtilosin A; Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. | 0.910 |
| albB | sboX | BSU37380 | BSU37360 | Putative membrane component involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for maximal production and for optimal immunity to subtilosin. | Putative bacteriocin-like product; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.898 |
| albC | albA | BSU37390 | BSU37370 | Putative transporter involved in subtilosin production; Involved in the production of the bacteriocin subtilosin. Required for immunity to subtilosin; Belongs to the ABC transporter superfamily. | Putative antilisterial bacteriocin (subtilosin) production enzyme; Catalyzes the formation of 3 thioether bonds during production of the sactipeptide subtilosin from SboA. In vitro the thioether bonds cannot be made in the absence of the SboA propeptide, suggesting this is the first reaction in subtilosin maturation. In vitro, in the absence of a second substrate, cleaves S-adenosyl-L-methionine into Met and 5'-dA. | 0.989 |
