STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ywdKConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0382 family. (123 aa)    
Predicted Functional Partners:
ybzI
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.848
yhfW
Putative Rieske [2Fe-2S] oxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
   
  
 0.833
ywfM
Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.830
ywdI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.647
comFB
Conserved hypothetical protein; Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16009133, 8045879, 8412657.
      
 0.634
ccpB
Transcriptional repressor of carbon supply (LacI family); Transcriptional regulator involved in catabolite repression of several operons.
      
 0.633
ywdJ
Putative purine/pyrimidine permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
  
    0.605
lipL
Octanoyl-[GcvH]:protein N-octanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
   
  
 0.576
phrH
Hexapeptide inhibitor of regulatory cascade; Inhibitor of the activity of phosphatase RapH. May inhibit the rapH promoter after import into the cytoplasm.
   
  
 0.575
comER
Putative pyrroline-5'-carboxylate reductase; Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase.
      
 0.574
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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