STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ywdAHypothetical protein; Evidence 5: No homology to any previously reported sequences. (82 aa)    
Predicted Functional Partners:
sacP
Phosphotransferase system (PTS) sucrose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport.
  
  
 0.913
sacA
Sucrase-6-phosphate hydrolase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the glycosyl hydrolase 32 family.
  
  
 0.892
sacX
Negative regulator of SacY; Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'. Negatively regulates SacY.
      
 0.849
yyzE
Putative phosphotransferase system enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
   
  
 0.760
ypqE
Putative phosphotransferase system enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
      
 0.706
gmuE
ROK fructokinase; Seems to be involved in the degradation of glucomannan.
   
  
 0.691
levB
Endolevanase; Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose; Belongs to the glycosyl hydrolase 32 family.
      
 0.485
mtlR
Transcriptional regulator; Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol.
   
  
 0.484
sacY
Transcriptional antiterminator; In the presence of sucrose, SacY is activated and prevents premature termination of transcription by binding to a RNA- antiterminator (RAT) sequence (partially overlapping with the terminator sequence) located upstream of the sacB gene. Formation of the SacY-RAT complex prevents alternative formation of the terminator, allowing transcription of the sacB gene. In the absence of sucrose, inhibition of SacY activity by SacX leads to termination of transcription; Belongs to the transcriptional antiterminator BglG family.
      
 0.475
sacB
Levansucrase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
   
  
 0.438
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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