STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (390 aa)    
Predicted Functional Partners:
galT
Galactose-1-phosphate uridyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
 
 0.999
galM
Aldose 1-epimerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the aldose epimerase family.
  
 0.998
galE
UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
 
 
 0.995
rpsL
Ribosomal protein S12 (BS12); With S4 and S5 plays an important role in translational accuracy.
   
  
 0.935
pta
Phosphotransacetylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
   
  
 0.790
sacB
Levansucrase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
      
 0.784
ganR
Transcriptional regulator (LacI family); Negatively regulates expression of ganA.
 
  
 0.743
yorC
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
      
 0.680
rapJ
Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
   
   0.642
spoIIIE
Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...]
   
    0.641
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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