| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| efeM | efeN | BSU38270 | BSU38260 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | 0.999 |
| efeM | efeU | BSU38270 | BSU38280 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | 0.999 |
| efeN | efeM | BSU38260 | BSU38270 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | 0.999 |
| efeN | efeU | BSU38260 | BSU38280 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | 0.998 |
| efeN | phoD | BSU38260 | BSU02620 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | 0.909 |
| efeN | tatAC | BSU38260 | BSU17710 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.816 |
| efeN | tatAY | BSU38260 | BSU05980 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion; Belongs to the TatA/E family. | 0.814 |
| efeN | tatCD | BSU38260 | BSU02640 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance; Belongs to the TatC family. | 0.826 |
| efeN | wapA | BSU38260 | BSU39230 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Cell wall-associated protein precursor; Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific general tRNA nuclease, the C-terminus (residues 2201-2334) removes 2 or 4 nucleotides from the 3' end of at least 4 tRNAs (upon expression in E.coli), possibly endonucleolytically. The nuclease activity is neutralized by expression of the cognate immunity protein WapI from the same strain, but not its homolog from 2 other B.subtilis strains. The C-terminus cannot be expressed on its own in E.coli, how [...] | 0.719 |
| efeN | ycnJ | BSU38260 | BSU03950 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family. | 0.932 |
| efeN | ykuE | BSU38260 | BSU14050 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallophosphoesterase superfamily. | 0.742 |
| efeN | yvgO | BSU38260 | BSU33410 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534. | 0.750 |
| efeU | efeM | BSU38280 | BSU38270 | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | 0.999 |
| efeU | efeN | BSU38280 | BSU38260 | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | 0.998 |
| efeU | tatAY | BSU38280 | BSU05980 | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion; Belongs to the TatA/E family. | 0.454 |
| efeU | tatCD | BSU38280 | BSU02640 | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance; Belongs to the TatC family. | 0.482 |
| phoD | efeN | BSU02620 | BSU38260 | Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | 0.909 |
| phoD | tatAC | BSU02620 | BSU17710 | Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.744 |
| phoD | tatAY | BSU02620 | BSU05980 | Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion; Belongs to the TatA/E family. | 0.636 |
| phoD | tatCD | BSU02620 | BSU02640 | Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance; Belongs to the TatC family. | 0.969 |
