| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| btr | efeM | BSU01640 | BSU38270 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | 0.562 |
| btr | efeU | BSU01640 | BSU38280 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | 0.641 |
| btr | feuA | BSU01640 | BSU01630 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Iron hydroxamate-binding lipoprotein; Involved in the uptake of iron. Belongs to the bacterial solute-binding protein 8 family. | 0.910 |
| btr | fhuD | BSU01640 | BSU33320 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Ferrichrome ABC transporter (ferrichrome-binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen. | 0.703 |
| btr | fhuG | BSU01640 | BSU33300 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Ferrichrome ABC transporter (permease); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity). | 0.829 |
| btr | yfiY | BSU01640 | BSU08440 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable). | 0.414 |
| btr | yfiZ | BSU01640 | BSU08450 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | iron(III) siderophore transport permease; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. | 0.762 |
| btr | yxeB | BSU01640 | BSU39610 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | ABC transporter (ferrioxamine binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine. | 0.606 |
| efeM | btr | BSU38270 | BSU01640 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | 0.562 |
| efeM | efeN | BSU38270 | BSU38260 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | 0.999 |
| efeM | efeU | BSU38270 | BSU38280 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | 0.999 |
| efeM | feuA | BSU38270 | BSU01630 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Iron hydroxamate-binding lipoprotein; Involved in the uptake of iron. Belongs to the bacterial solute-binding protein 8 family. | 0.542 |
| efeM | fhuD | BSU38270 | BSU33320 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Ferrichrome ABC transporter (ferrichrome-binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen. | 0.641 |
| efeM | fhuG | BSU38270 | BSU33300 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Ferrichrome ABC transporter (permease); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity). | 0.501 |
| efeM | yfiY | BSU38270 | BSU08440 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable). | 0.646 |
| efeM | yxeB | BSU38270 | BSU39610 | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | ABC transporter (ferrioxamine binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine. | 0.553 |
| efeN | efeM | BSU38260 | BSU38270 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Lipoprotein binding ferrous or ferric iron for transport; Involved in iron uptake; Belongs to the EfeM/EfeO family. | 0.999 |
| efeN | efeU | BSU38260 | BSU38280 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Ferrous ion permease; Uptake of Fe(2+) ions across the membrane. | 0.998 |
| efeN | folN | BSU38260 | BSU24890 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | 5-formyltetrahydrofolate cyclo-ligase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.637 |
| efeN | yfiY | BSU38260 | BSU08440 | Peroxidase converting ferric iron into ferrous iron; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). | Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable). | 0.543 |
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