STRINGSTRING
epr protein (Bacillus subtilis) - STRING interaction network
"epr" - Minor extracellular protease Epr in Bacillus subtilis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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[Homology]
Score
eprMinor extracellular protease Epr; Evidence 1a- Function experimentally demonstrated in the studied strain; Product type e- enzyme; Belongs to the peptidase S8 family (645 aa)    
Predicted Functional Partners:
mpr
Extracellular metalloprotease; Evidence 1c- Function experimentally demonstrated in the studied genus; Product type e- enzyme; Belongs to the peptidase S1B family (313 aa)
 
     
  0.936
nprB
Neutral protease B; Protease able to cleave casein in vitro; Belongs to the peptidase M4 family (538 aa)
 
 
   
  0.915
vpr
Minor extracellular protease vpr; Not required for growth or sporulation (806 aa)
   
   
0.905
nprE
Bacillolysin; Extracellular zinc metalloprotease; Belongs to the peptidase M4 family (521 aa)
 
 
   
  0.862
aprE
Subtilisin E; Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides; Belongs to the peptidase S8 family (381 aa)
   
   
0.846
ypjA
Uncharacterized protein YpjA; Evidence 3- Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm- putative membrane component (185 aa)
           
  0.742
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5’-TGNCGAA-3’ (0A box) (267 aa)
   
     
  0.632
htrB
Serine protease Do-like HtrB; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family (458 aa)
   
   
  0.591
wprA
Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family (894 aa)
   
     
0.569
sigD
RNA polymerase sigma-D factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis (254 aa)
           
  0.547
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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