Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yxlENegative regulator of sigma-Y activity; Together with YxlD is important for negative regulation of sigma Y activity. (62 aa)    
Predicted Functional Partners:
yxlD
Putative sigma-Y antisigma factor component; Together with YxlE, is important for negative regulation of sigma Y activity, being the major negative regulator.
  
  
 0.999
yxlC
sigma-Y antisigma factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
  
  
 0.997
sigY
RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY-yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB.
 
  
 0.991
yxlG
Putative ABC-transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
    0.989
yxlF
Putative ABC transporter component (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
    0.986
ybgB
Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008.
  
  
 0.910
bglC
Aryl-phospho-beta-d-glucosidase; Is able to catalyze the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source. Belongs to the glycosyl hydrolase 1 family.
      
 0.906
xhlA
Defective prophage PBSX putative enzyme; Associated with cell lysis upon induction of PbsX; To B.licheniformis xpaF1 and xpaL1.
      
 0.782
ygxA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.708
yjbC
Putative thiol oxidation management factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
    0.583
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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