| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| btr | yxkI | BSU01640 | BSU38780 | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.413 |
| cimH | yxkI | BSU38770 | BSU38780 | citrate/malate/H+ symporter; Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective, translocating only the (S)-enantiomer of malate. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.504 |
| csfB | ybcI | BSU00240 | BSU01880 | Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment. Overexpression also inhibits sigma- G transcription activation activity. When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.400 |
| csfB | yxkI | BSU00240 | BSU38780 | Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment. Overexpression also inhibits sigma- G transcription activation activity. When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.497 |
| grpE | yxkI | BSU25480 | BSU38780 | Nucleotide exchange factor for DnaK activity; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.404 |
| ybcI | csfB | BSU01880 | BSU00240 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment. Overexpression also inhibits sigma- G transcription activation activity. When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction. | 0.400 |
| ybcI | yxkI | BSU01880 | BSU38780 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.459 |
| ydbT | yxkI | BSU04600 | BSU38780 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.402 |
| ykzQ | yxkI | BSU13789 | BSU38780 | Putative peptidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.505 |
| yteT | yxkI | BSU30100 | BSU38780 | Putative dehydrogenase of rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the Gfo/Idh/MocA family. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.499 |
| ywpF | yxkI | BSU36330 | BSU38780 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | 0.402 |
| yxkI | btr | BSU38780 | BSU01640 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin. | 0.413 |
| yxkI | cimH | BSU38780 | BSU38770 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | citrate/malate/H+ symporter; Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective, translocating only the (S)-enantiomer of malate. | 0.504 |
| yxkI | csfB | BSU38780 | BSU00240 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment. Overexpression also inhibits sigma- G transcription activation activity. When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction. | 0.497 |
| yxkI | grpE | BSU38780 | BSU25480 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Nucleotide exchange factor for DnaK activity; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...] | 0.404 |
| yxkI | ybcI | BSU38780 | BSU01880 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.459 |
| yxkI | ydbT | BSU38780 | BSU04600 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.402 |
| yxkI | ykzQ | BSU38780 | BSU13789 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Putative peptidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. | 0.505 |
| yxkI | yteT | BSU38780 | BSU30100 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Putative dehydrogenase of rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the Gfo/Idh/MocA family. | 0.499 |
| yxkI | ywpF | BSU38780 | BSU36330 | Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M48 family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.402 |