node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysC | mccB | BSU15600 | BSU27250 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | 0.620 |
cysC | tcyP | BSU15600 | BSU09130 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.729 |
cysC | yxeK | BSU15600 | BSU39520 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.524 |
cysC | yxeL | BSU15600 | BSU39510 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.502 |
cysC | yxeM | BSU15600 | BSU39500 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.552 |
cysC | yxeN | BSU15600 | BSU39490 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.526 |
cysC | yxeO | BSU15600 | BSU39480 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.613 |
cysC | yxeP | BSU15600 | BSU39470 | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | Putative amidohydrolase; Probably catalyzes the deacetylation of N-acetylcysteine (NAC) to acetate and cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Belongs to the peptidase M20 family. | 0.768 |
mccB | cysC | BSU27250 | BSU15600 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | 0.620 |
mccB | tcyP | BSU27250 | BSU09130 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.878 |
mccB | yxeK | BSU27250 | BSU39520 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.696 |
mccB | yxeL | BSU27250 | BSU39510 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.515 |
mccB | yxeM | BSU27250 | BSU39500 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.543 |
mccB | yxeN | BSU27250 | BSU39490 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.579 |
mccB | yxeO | BSU27250 | BSU39480 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.590 |
mccB | yxeP | BSU27250 | BSU39470 | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | Putative amidohydrolase; Probably catalyzes the deacetylation of N-acetylcysteine (NAC) to acetate and cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Belongs to the peptidase M20 family. | 0.736 |
tcyP | cysC | BSU09130 | BSU15600 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family. | 0.729 |
tcyP | mccB | BSU09130 | BSU27250 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide. | 0.878 |
tcyP | yxeK | BSU09130 | BSU39520 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.797 |
tcyP | yxeL | BSU09130 | BSU39510 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.677 |