| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| tcyK | ytlI | BSU29370 | BSU29400 | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | 0.772 |
| tcyK | yxeL | BSU29370 | BSU39510 | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.699 |
| tcyK | yxeM | BSU29370 | BSU39500 | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.450 |
| tcyK | yxeN | BSU29370 | BSU39490 | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.843 |
| tcyK | yxeO | BSU29370 | BSU39480 | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.758 |
| tcyP | ytlI | BSU09130 | BSU29400 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | 0.608 |
| tcyP | yxeK | BSU09130 | BSU39520 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.724 |
| tcyP | yxeL | BSU09130 | BSU39510 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.690 |
| tcyP | yxeM | BSU09130 | BSU39500 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.726 |
| tcyP | yxeN | BSU09130 | BSU39490 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.728 |
| tcyP | yxeO | BSU09130 | BSU39480 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.727 |
| tcyP | yxeP | BSU09130 | BSU39470 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative amidohydrolase; Probably catalyzes the deacetylation of N-acetylcysteine (NAC) to acetate and cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Belongs to the peptidase M20 family. | 0.647 |
| tcyP | yxeQ | BSU09130 | BSU39460 | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Putative catabolic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the PrpD family. | 0.634 |
| ytlI | tcyK | BSU29400 | BSU29370 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family. | 0.772 |
| ytlI | tcyP | BSU29400 | BSU09130 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.608 |
| ytlI | yxeK | BSU29400 | BSU39520 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.732 |
| ytlI | yxeL | BSU29400 | BSU39510 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.904 |
| ytlI | yxeM | BSU29400 | BSU39500 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.566 |
| ytlI | yxeN | BSU29400 | BSU39490 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.460 |
| ytlI | yxeO | BSU29400 | BSU39480 | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.496 |
