STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yxdMABC transporter (permease); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance; Belongs to the ABC-4 integral membrane protein family. (622 aa)    
Predicted Functional Partners:
yclH
Putative ABC transporter (ATPase component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.
 
 
 0.988
yxdK
Two-component sensor histidine kinase [YxdJ]; Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37.
 
  
 0.981
yxdL
ABC transporter (ATP-binding protein); Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Responsible for energy coupling to the transport system (Probable).
 
 0.974
ytrF
Metabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
  
  
 0.874
yvcR
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.
 
 0.866
yxdJ
Two-component response regulator [YxdK]; Probable member of the two-component regulatory system YxdK/YxdJ. Positively regulates the expression of the yxdLMyxeA operon by direct interaction with its promoter region. Could also indirectly regulate the expression of the dlt operon.
 
    0.859
yxeA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
    0.848
bceA
Bacitracin ABC efflux transporter (ATP-binding protein); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export. Responsible for energy coupling to the transport system.
 
 0.816
yvcQ
Two-component sensor histidine kinase [YvcP]; Member of the two-component regulatory system YvcQ/YvcP. Probably activates YvcP by phosphorylation.
 
    0.778
yvcP
Two-component response regulator [YvcQ]; Member of the two-component regulatory system YvcQ/YvcP.
 
     0.733
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.