STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yxaDPutative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator. (143 aa)    
Predicted Functional Partners:
qdoR
Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
   
  
 0.980
yxaC
Putative murein hydrolase export regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
  
 0.963
yxaH
Putative integral inner membrane protein; Involved in transport.
   
  
 0.921
qodI
Quercetin dioxygenase; Performs the first step in the degradation of the flavonoid quercetin by a dioxygenase reaction. The enzyme catalyzes the cleavage of the O-heteroaromatic ring of the flavonol quercetin yielding the depside 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. This involves the remarkable dioxygenolytic cleavage of two carbon-carbon bonds.
  
  
 0.918
yfmO
Metal efflux transporter; Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance. Belongs to the major facilitator superfamily.
 
    0.757
yxzK
Putative integral inner membrane protein involved in export murein hydrolases; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
    0.567
yraI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YraJ.
  
     0.554
ywbG
Anti-holin factor controlling activity of murein hydrolases; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
 0.523
lrgB
Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
     
 0.507
bsn
Extracellular ribonuclease; Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate.
  
     0.492
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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