node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
htrC | walH | BSU40360 | BSU40390 | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | 0.917 |
htrC | walJ | BSU40360 | BSU40370 | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-beta-lactamase superfamily. | 0.954 |
htrC | walK | BSU40360 | BSU40400 | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Phosphorylates WalR. | 0.874 |
htrC | walR | BSU40360 | BSU40410 | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | Two-component response regulator [YycF]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA. | 0.891 |
htrC | yycI | BSU40360 | BSU40380 | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | Regulator of YycFG; Together with YycH, regulates the activity of the two- component system WalR/WalK. | 0.909 |
phoR | resE | BSU29100 | BSU23110 | Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | 0.491 |
phoR | walK | BSU29100 | BSU40400 | Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. | Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Phosphorylates WalR. | 0.463 |
phoR | walR | BSU29100 | BSU40410 | Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. | Two-component response regulator [YycF]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA. | 0.961 |
resE | phoR | BSU23110 | BSU29100 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. | 0.491 |
resE | walK | BSU23110 | BSU40400 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Phosphorylates WalR. | 0.418 |
resE | walR | BSU23110 | BSU40410 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Two-component response regulator [YycF]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA. | 0.952 |
resE | yclK | BSU23110 | BSU03760 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Two-component sensor histidine kinase [YclJ]; Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ. | 0.422 |
walH | htrC | BSU40390 | BSU40360 | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | 0.917 |
walH | walJ | BSU40390 | BSU40370 | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-beta-lactamase superfamily. | 0.992 |
walH | walK | BSU40390 | BSU40400 | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Phosphorylates WalR. | 0.999 |
walH | walR | BSU40390 | BSU40410 | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | Two-component response regulator [YycF]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA. | 0.992 |
walH | yycI | BSU40390 | BSU40380 | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | Regulator of YycFG; Together with YycH, regulates the activity of the two- component system WalR/WalK. | 0.999 |
walJ | htrC | BSU40370 | BSU40360 | Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-beta-lactamase superfamily. | Putative sensor protein; Evidence 7: Gene remnant; Product type pr: putative regulator. | 0.954 |
walJ | walH | BSU40370 | BSU40390 | Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-beta-lactamase superfamily. | Regulator of YycFG; Together with YycI, regulates the activity of the two- component system WalR/WalK. | 0.992 |
walJ | walK | BSU40370 | BSU40400 | Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-beta-lactamase superfamily. | Two-component sensor histidine kinase [YycG]; Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Phosphorylates WalR. | 0.987 |