STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yyaNPutative transcriptional regulator (MerR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (138 aa)    
Predicted Functional Partners:
yfmO
Metal efflux transporter; Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance. Belongs to the major facilitator superfamily.
      
 0.919
yyaO
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
  
 0.915
cueR
Copper efflux transcriptional regulator; Transcriptional activator of the copZA operon.
  
   
 0.852
ygaO
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
      
 0.849
ykqA
Conserved hypothetical protein; Putative gamma-glutamylcyclotransferase.
      
 0.849
yraO
Putative citrate transporter; Transports the free citrate anion; Belongs to the CitM (TC 2.A.11) transporter family.
      
 0.849
yyaM
Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
    0.805
yflI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.686
mta
Transcriptional regulator (MerR family); Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE.
  
    0.657
copZ
Copper insertion chaperone and transporter component; Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Functions in E.coli to transfer Cu(+) to CopA missing its first metal-binding domain.
  
  
 0.622
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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