col protein (Aquifex aeolicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

Experiments

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[Homology]

Score

col

Collagenase. (409 aa)

Predicted Functional Partners:

aq_1085

0.719

omt

0.719

ribH

0.687

pilC2

0.609

lgtF

0.609

dnaK

0.603

tpx

0.601

aq_1017

0.553

aq_1018

0.553

nadA

0.471

Your Current Organism:

Aquifex aeolicus

NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aq_1017	aq_1018	aq_1017	aq_1018	Putative protein.	Putative protein.	0.773
aq_1017	col	aq_1017	aq_1015	Putative protein.	Collagenase.	0.553
aq_1018	aq_1017	aq_1018	aq_1017	Putative protein.	Putative protein.	0.773
aq_1018	col	aq_1018	aq_1015	Putative protein.	Collagenase.	0.553
aq_1085	col	aq_1085	aq_1015	Putative protein.	Collagenase.	0.719
col	aq_1017	aq_1015	aq_1017	Collagenase.	Putative protein.	0.553
col	aq_1018	aq_1015	aq_1018	Collagenase.	Putative protein.	0.553
col	aq_1085	aq_1015	aq_1085	Collagenase.	Putative protein.	0.719
col	dnaK	aq_1015	aq_996	Collagenase.	Hsp70 chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.603
col	lgtF	aq_1015	aq_1742	Collagenase.	Beta 1,4 glucosyltransferase.	0.609
col	nadA	aq_1015	aq_1889	Collagenase.	Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.	0.471
col	omt	aq_1015	aq_1507	Collagenase.	O-methyltransferase.	0.719
col	pilC2	aq_1015	aq_1285	Collagenase.	Fimbrial assembly protein PilC2.	0.609
col	ribH	aq_1015	aq_132	Collagenase.	Riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.687
col	tpx	aq_1015	aq_488	Collagenase.	Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.	0.601
dnaK	col	aq_996	aq_1015	Hsp70 chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Collagenase.	0.603
dnaK	tpx	aq_996	aq_488	Hsp70 chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.	0.598
lgtF	col	aq_1742	aq_1015	Beta 1,4 glucosyltransferase.	Collagenase.	0.609
lgtF	nadA	aq_1742	aq_1889	Beta 1,4 glucosyltransferase.	Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.	0.608
lgtF	pilC2	aq_1742	aq_1285	Beta 1,4 glucosyltransferase.	Fimbrial assembly protein PilC2.	0.740