aq_1024 protein (Aquifex aeolicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

aq_1024

Hypothetical protein. (281 aa)

Predicted Functional Partners:

gyrB

0.796

acuC1

0.773

aq_1029

0.741

aq_855

0.682

ogt

0.443

selD

0.411

selA

0.400

Your Current Organism:

Aquifex aeolicus

NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acuC1	aq_1024	aq_1023	aq_1024	Acetoin utilization protein.	Hypothetical protein.	0.773
acuC1	aq_1029	aq_1023	aq_1029	Acetoin utilization protein.	Putative protein.	0.741
acuC1	gyrB	aq_1023	aq_1026	Acetoin utilization protein.	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	0.796
acuC1	selD	aq_1023	aq_1030	Acetoin utilization protein.	Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.	0.402
aq_1024	acuC1	aq_1024	aq_1023	Hypothetical protein.	Acetoin utilization protein.	0.773
aq_1024	aq_1029	aq_1024	aq_1029	Hypothetical protein.	Putative protein.	0.741
aq_1024	aq_855	aq_1024	aq_855	Hypothetical protein.	Hypothetical protein.	0.682
aq_1024	gyrB	aq_1024	aq_1026	Hypothetical protein.	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	0.796
aq_1024	ogt	aq_1024	aq_1495	Hypothetical protein.	O-6-methylguanine-DNA-alkyltransferase.	0.443
aq_1024	selA	aq_1024	aq_1031	Hypothetical protein.	L-seryl-tRNA(ser) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.	0.400
aq_1024	selD	aq_1024	aq_1030	Hypothetical protein.	Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.	0.411
aq_1029	acuC1	aq_1029	aq_1023	Putative protein.	Acetoin utilization protein.	0.741
aq_1029	aq_1024	aq_1029	aq_1024	Putative protein.	Hypothetical protein.	0.741
aq_1029	gyrB	aq_1029	aq_1026	Putative protein.	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	0.741
aq_1029	selD	aq_1029	aq_1030	Putative protein.	Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.	0.416
aq_855	aq_1024	aq_855	aq_1024	Hypothetical protein.	Hypothetical protein.	0.682
aq_855	ogt	aq_855	aq_1495	Hypothetical protein.	O-6-methylguanine-DNA-alkyltransferase.	0.443
gyrB	acuC1	aq_1026	aq_1023	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	Acetoin utilization protein.	0.796
gyrB	aq_1024	aq_1026	aq_1024	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	Hypothetical protein.	0.796
gyrB	aq_1029	aq_1026	aq_1029	Gyrase B; A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. If this subunit is reconstituted with GyrA from E.coli the hybrid enzyme supercoils relaxed plasmid DNA; if paired with E.coli ParC supercoiling is not restored. This the first bacteria shown to not contain DNA gyrase, although it has 2 copies of a reverse gyrase that introduces positive supercoils. Type II topoisomera [...]	Putative protein.	0.741