STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdx3Ferredoxin. (79 aa)    
Predicted Functional Partners:
forB1
Ferredoxin oxidoreductase beta subunit.
  
 
 0.918
forA1
Ferredoxin oxidoreductase alpha subunit.
  
 
 0.907
forG1
Ferredoxin oxidoreductase gamma subunit.
  
  
 0.770
mdh2
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
      
 0.757
mdh1
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
      
 0.757
aq_1192
Putative protein.
       0.747
sucD2
succinyl-CoA ligase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
      
 0.747
aq_1194
Putative protein.
       0.746
sucC1
succinyl-CoA ligase beta subunit.
      
 0.739
frdA
Fumarate reductase flavoprotein subunit.
      
 0.737
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.