Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
czcB2Cation efflux system (czcB-like); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (348 aa)    
Predicted Functional Partners:
aq_1332
Hypothetical protein.
 
  0.991
acrD4
Cation efflux (AcrB/AcrD/AcrF family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.984
acrD1
Cation efflux system (AcrB/AcrD/AcrF family); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.964
aq_699
Hypothetical protein.
  
  0.956
aq_986
Putative protein.
  
  
  0.954
aq_1059
Putative protein.
 
  0.950
acrE
Acriflavin resistance protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.929
aq_1093
Putative protein.
   
  0.928
aq_1133
Putative protein.
   
  0.928
aq_1670
Putative protein.
   
  0.928
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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