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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutT8-OXO-dGTPase domain (mutT domain); Belongs to the Nudix hydrolase family. (139 aa)    
Predicted Functional Partners:
imp2
Myo-inositol-1(or 4)-monophosphatase; Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1- phosphate (I-1-P); Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.
 
    0.903
argH
Argininosuccinate lyase.
 
      0.899
hisIE
phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family.
     
 0.838
aq_1446
Putative protein.
 
     0.794
aq_1447
Hypothetical protein.
       0.773
nfo
Deoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
     
 0.756
pfpI
Protease I.
      
 0.750
aq_1292
Hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency. Does not have kinase activity; Belongs to the THEP1 NTPase family.
      
 0.739
apfA
AP4A hydrolase; Belongs to the Nudix hydrolase family.
      
 0.737
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.662
Your Current Organism:
Aquifex aeolicus
NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5
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