aco protein (Aquifex aeolicus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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[Homology]

Score

aco

Aconitase. (659 aa)

Predicted Functional Partners:

gltA

0.994

mdh1

0.969

icd

0.964

leuB

0.939

hoxX

0.902

atpA

0.877

mdh2

0.870

fumB

0.865

rpmF

0.847

sodA

0.847

Your Current Organism:

Aquifex aeolicus

NCBI taxonomy Id: 224324
Other names: A. aeolicus VF5, Aquifex aeolicus VF5, Aquifex aeolicus str. VF5

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aco	atpA	aq_1784	aq_679	Aconitase.	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	0.877
aco	fumB	aq_1784	aq_1780	Aconitase.	Fumarate hydratase (fumarase).	0.865
aco	gltA	aq_1784	aq_150	Aconitase.	Citrate synthase.	0.994
aco	hoxX	aq_1784	aq_1156	Aconitase.	Hydrogenase regulation HoxX; Belongs to the enoyl-CoA hydratase/isomerase family.	0.902
aco	icd	aq_1784	aq_1512	Aconitase.	Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.964
aco	leuB	aq_1784	aq_244	Aconitase.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.	0.939
aco	mdh1	aq_1784	aq_1782	Aconitase.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.969
aco	mdh2	aq_1784	aq_1665	Aconitase.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.	0.870
aco	rpmF	aq_1784	aq_1102	Aconitase.	Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.847
aco	sodA	aq_1784	aq_1499	Aconitase.	Superoxide dismutase (Fe/Mn family); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.	0.847
atpA	aco	aq_679	aq_1784	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Aconitase.	0.877
atpA	gltA	aq_679	aq_150	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Citrate synthase.	0.888
atpA	hoxX	aq_679	aq_1156	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Hydrogenase regulation HoxX; Belongs to the enoyl-CoA hydratase/isomerase family.	0.480
atpA	icd	aq_679	aq_1512	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.710
atpA	leuB	aq_679	aq_244	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.	0.628
atpA	mdh1	aq_679	aq_1782	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.813
atpA	mdh2	aq_679	aq_1665	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.	0.813
atpA	rpmF	aq_679	aq_1102	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.709
atpA	sodA	aq_679	aq_1499	ATP synthase F1 alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.	Superoxide dismutase (Fe/Mn family); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.	0.514
fumB	aco	aq_1780	aq_1784	Fumarate hydratase (fumarase).	Aconitase.	0.865