STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0035Mannosephosphate isomerase, putative; Similar to GB:D16594 PID:451216 SP:Q59935 percent identity: 31.30; identified by sequence similarity; putative. (299 aa)    
Predicted Functional Partners:
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
  
 
 0.965
AF_1097
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase (manC); Similar to PID:559389 percent identity: 43.08; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.951
AF_1494
Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative.
    
  0.932
queD
Conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
     
 0.905
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
AF_0242
Glucose-1-phosphate thymidylyltransferase (graD-1); Similar to PID:763512 percent identity: 27.69; identified by sequence similarity; putative.
 
 
 0.669
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.668
AF_0444
Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
 
  
 0.639
AF_1968
Transcriptional regulatory protein, Rok family; Similar to PID:1208894 SP:Q44406 percent identity: 32.91; identified by sequence similarity; putative.
  
  
 0.587
aqpM
Glycerol uptake facilitator, MIP channel (glpF); Channel that permits osmotically driven movement of water in both directions.
  
  
 0.463
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.