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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
matConserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (399 aa)    
Predicted Functional Partners:
AF_2112
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Similar to PID:1103707 SP:P55299 percent identity: 28.08; identified by sequence similarity; putative.
     
 0.922
speH
Conserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
     
 0.916
AF_0049
Predicted coding region AF_0049; Hypothetical protein; identified by GeneMark; putative.
       0.576
AF_1988
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57692 PID:1499018 percent identity: 42.77; identified by sequence similarity; putative.
 
     0.517
AF_1972
Conserved hypothetical protein; Similar to GB:L77117 PID:1500551 percent identity: 30.07; identified by sequence similarity; putative.
 
     0.470
AF_0048
Predicted coding region AF_0048; Hypothetical protein; identified by GeneMark; putative.
       0.459
AF_0587
Conserved hypothetical protein; Similar to GB:L77117 PID:1499864 percent identity: 31.13; identified by sequence similarity; putative.
  
     0.458
AF_1989
Peptidyl-prolyl cis-trans isomerase (slyD); Similar to GB:L77117 SP:Q58235 PID:1591512 percent identity: 34.38; identified by sequence similarity; putative.
  
  
 0.447
AF_2068
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58103 PID:1591406 percent identity: 53.27; identified by sequence similarity; putative; Belongs to the PDCD5 family.
  
    0.446
hisG
ATP phosphoribosyltransferase (hisG); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
    0.441
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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