Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_0055Conserved hypothetical protein; Similar to GB:L77117 PID:1592056 percent identity: 48.00; identified by sequence similarity; putative; Belongs to the UPF0107 family. (132 aa)    
Predicted Functional Partners:
AF_2333
Conserved hypothetical protein; Similar to GB:L77117 PID:1591952 percent identity: 45.50; identified by sequence similarity; putative.
 
 
 0.999
AF_0053
Conserved hypothetical protein; Similar to PID:1001613 percent identity: 41.63; identified by sequence similarity; putative.
 
     0.908
mvk
Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.902
AF_0054
Predicted coding region AF_0054; Hypothetical protein; identified by GeneMark; putative.
       0.811
rpoP
Predicted coding region AF_0056; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
       0.719
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
       0.718
AF_0058
Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family.
 
     0.664
tmk
Thymidylate kinase (tmk); Similar to SP:P37345 PID:1244710 GB:U00096 PID:1787340 percent identity: 34.87; identified by sequence similarity; putative.
       0.655
AF_0059
Predicted coding region AF_0059; Hypothetical protein; identified by GeneMark; putative.
       0.607
AF_2200
Mutator protein MutT, putative; Similar to GB:L77117 PID:1500003 percent identity: 41.98; identified by sequence similarity; putative.
       0.563
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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