Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_0058Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. (174 aa)    
Predicted Functional Partners:
AF_1106
Conserved hypothetical protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.971
rpl10
LSU ribosomal protein L10E (rpl10E); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.970
AF_0428
GTP-binding protein, GTP1/OBG-family; Similar to GB:L77117 PID:1592057 percent identity: 43.92; identified by sequence similarity; putative.
   
 
 0.968
rps8e
SSU ribosomal protein S8E (rps8E); Similar to GB:L77117 SP:P54055 PID:1591387 percent identity: 61.60; identified by sequence similarity; putative.
  
 
 0.961
rpl30
LSU ribosomal protein L30P (rpl30P); Similar to GB:L77117 SP:P54046 PID:1591178 percent identity: 55.92; identified by sequence similarity; putative.
   
 
 0.956
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
 
 
 0.955
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
 
 0.955
rpl7ae
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.947
AF_2088
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative.
  
 0.928
rlmE
Cell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
 
 0.927
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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