Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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cas5Predicted coding region AF_0067; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). (228 aa)    
Predicted Functional Partners:
AF_0071
ATP-dependent RNA helicase, putative; Similar to GB:L77117 SP:Q57828 PID:1591089 percent identity: 29.59; identified by sequence similarity; putative.
  
 
 0.972
AF_0068
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57826 PID:1591087 percent identity: 26.95; identified by sequence similarity; putative.
  
 
 0.949
AF_0069
Predicted coding region AF_0069; Hypothetical protein; identified by GeneMark; putative.
       0.800
AF_0070
Predicted coding region AF_0070; Hypothetical protein; identified by GeneMark; putative.
       0.800
AF_1871
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57826 PID:1591087 percent identity: 27.33; identified by sequence similarity; putative.
  
 
 0.795
AF_1874
Predicted coding region AF_1874; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.756
AF_0072
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
     
 0.588
AF_1875
Predicted coding region AF_1875; Hypothetical protein; identified by GeneMark; putative.
   
   0.551
trpE
Anthranilate synthase component I (trpE) {Methanococcus jannaschii); Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly [...]
     
 0.540
AF_0065
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58384 PID:1591637 percent identity: 29.77; identified by sequence similarity; putative.
       0.498
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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