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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0084Predicted coding region AF_0084; Hypothetical protein; identified by GeneMark; putative. (151 aa)    
Predicted Functional Partners:
AF_0083
Predicted coding region AF_0083; Hypothetical protein; identified by GeneMark; putative.
       0.777
AF_0085
Predicted coding region AF_0085; Hypothetical protein; identified by GeneMark; putative.
       0.572
cobB2
Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
    0.509
cobB1
Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
    0.509
AF_1488
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family.
  
    0.463
AF_2315
Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative.
  
    0.463
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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