Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_00912-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE-1); Similar to GB:L77117 PID:1500558 percent identity: 44.51; identified by sequence similarity; putative. (324 aa)    
Predicted Functional Partners:
AF_0090
Dehydrase; Similar to GB:X63449 PID:46810 percent identity: 34.15; identified by sequence similarity; putative.
 
    0.978
AF_0089
long-chain-fatty-acid--CoA ligase (fadD-1); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 31.91; identified by sequence similarity; putative.
  
  
 0.657
AF_2101
Alcohol dehydrogenase, zinc-dependent; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 30.06; identified by sequence similarity; putative.
 
 
 0.488
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.431
AF_1207
2-deoxy-D-gluconate 3-dehydrogenase (kduD); Similar to SP:Q05528 GB:X62073 PID:48986 percent identity: 45.31; identified by sequence similarity; putative.
 
 
 0.417
AF_0088
Thiamine biosynthesis protein, putative; Similar to GB:L42023 SP:P44658 PID:1003600 PID:1222282 PID:1204606 percent identity: 28.17; identified by sequence similarity; putative.
  
  
 0.405
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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