Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0125Conserved hypothetical protein; Similar to GB:L77117 SP:Q57951 PID:1591234 percent identity: 22.14; identified by sequence similarity; putative. (167 aa)    
Predicted Functional Partners:
AF_0211
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58799 PID:1592053 percent identity: 30.77; identified by sequence similarity; putative.
  
    0.572
AF_0124
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57883 PID:1591145 percent identity: 26.29; identified by sequence similarity; putative.
     
 0.531
AF_0123
Predicted coding region AF_0123; Hypothetical protein; identified by GeneMark; putative.
       0.527
ogt
methylated-DNA-protein-cysteine methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.496
AF_0062
Conserved hypothetical protein; Similar to PID:688456 percent identity: 42.55; identified by sequence similarity; putative.
  
    0.459
AF_0848
Conserved hypothetical protein; Similar to GB:L77117 PID:1591856 percent identity: 34.78; identified by sequence similarity; putative.
  
    0.459
AF_1341
Thymidine phosphorylase (deoA-1); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
  
    0.410
AF_1342
Thymidine phosphorylase (deoA-2); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
  
    0.410
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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