Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0167Flavoprotein (fprA-1); Similar to GB:L77117 SP:Q58142 PID:1591446 percent identity: 33.23; identified by sequence similarity; putative. (336 aa)    
Predicted Functional Partners:
AF_0951
NADH oxidase (noxA-4); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 36.71; identified by sequence similarity; putative.
    
 0.919
feR
Conserved hypothetical protein; Catalyzes the reduction of bound ferric iron (Fe(3+)) in a variety of iron chelators (siderophores) using NAD(P)H as the electron donor, resulting in the release of Fe(2+). Not active with uncomplexed Fe(3+). Also reduces FMN and FAD, but not riboflavin. Belongs to the non-flavoprotein flavin reductase family.
    
 0.915
AF_0395
NADH oxidase (noxA-2); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.45; identified by sequence similarity; putative.
    
 0.893
AF_0833
Desulfoferrodoxin (dfx); Similar to GB:M81168 SP:P20418 GB:M28848 PID:145115 PID:758676 percent identity: 63.03; identified by sequence similarity; putative; Belongs to the desulfoferrodoxin family.
 
  
 0.850
AF_0166
Ferredoxin (fdx-2); Similar to SP:P29604 percent identity: 49.15; identified by sequence similarity; putative.
     
 0.792
AF_0170
Predicted coding region AF_0170; Hypothetical protein; identified by GeneMark; putative.
 
   
 0.695
AF_0834
Ferritin, putative; Similar to GB:L42023 SP:P43707 PID:1007431 PID:1221522 PID:1205619 percent identity: 39.75; identified by sequence similarity; putative.
  
  
 0.677
AF_0270
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.675
AF_0344
Desulfoferrodoxin, putative; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
 
  
 0.655
AF_2312
Rubrerythrin (rr4); Similar to GB:M77011 SP:P24931 PID:145124 PID:1769571 percent identity: 41.36; identified by sequence similarity; putative.
 
  
 0.628
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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