Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0177Tungsten formylmethanofuran dehydrogenase, subunit E (fwdE); Similar to GP:1702945 percent identity: 29.75; identified by sequence similarity; putative. (189 aa)    
Predicted Functional Partners:
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
  
    0.773
AF_0174
Molybdopterin oxidoreductase, membrane subunit; Similar to SP:P31077 GB:X65042 PID:48528 percent identity: 26.03; identified by sequence similarity; putative.
 
     0.656
AF_0176
Molybdopterin oxidoreductase, molybdopterin binding subunit; Similar to SP:P09152 GB:X16181 GB:X01164 GB:X15996 PID:146926 percent identity: 32.57; identified by sequence similarity; putative.
  
    0.653
AF_0432
Iron (III) ABC transporter, ATP-binding protein (hemV-2); Similar to GB:L77117 SP:Q57550 PID:1590868 percent identity: 58.71; identified by sequence similarity; putative.
 
    0.604
AF_0175
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Similar to SP:P31076 GB:X65042 PID:48527 percent identity: 42.02; identified by sequence similarity; putative.
       0.600
AF_0173
Reductase, assembly protein; Similar to GB:Z26255 percent identity: 30.00; identified by sequence similarity; putative.
       0.598
AF_1649
Tungsten formylmethanofuran dehydrogenase, subunit G (fwdG); Similar to PID:871460 GB:AE000666 PID:1890208 percent identity: 45.57; identified by sequence similarity; putative.
  
   
 0.596
AF_0010
Predicted coding region AF_0010; Hypothetical protein; identified by GeneMark; putative.
  
   
 0.532
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
   
  
 0.524
AF_0918
Pyruvate formate-lyase activating enzyme (act-2); Similar to GB:L77117 SP:Q58214 PID:1499627 percent identity: 42.65; identified by sequence similarity; putative.
  
   
 0.514
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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