Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0180Predicted coding region AF_0180; Hypothetical protein; identified by GeneMark; putative. (286 aa)    
Predicted Functional Partners:
AF_0181
Conserved hypothetical protein; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
 
     0.927
AF_0183
Conserved hypothetical protein; Similar to SP:P54432 PID:1303704 GB:AL009126 percent identity: 32.11; identified by sequence similarity; putative.
 
     0.773
AF_0182
Predicted coding region AF_0182; Hypothetical protein; identified by GeneMark; putative.
       0.633
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.618
AF_1644
Tungsten formylmethanofuran dehydrogenase, subunit F (fwdF); Similar to GB:L77117 PID:1591792 percent identity: 38.21; identified by sequence similarity; putative.
 
     0.565
AF_0009
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase (mtr) {Methanobacterium thermoautotro; Similar to PID:668979 GB:AE000666 percent identity: 42.09; identified by sequence similarity; putative.
  
     0.558
AF_0187
Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.
 
     0.549
AF_0184
Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.
 
     0.519
sepS
Conserved hypothetical protein; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys); Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
 
     0.481
AF_0934
Conserved hypothetical protein; Similar to GB:L77117 PID:1500498 percent identity: 31.88; identified by sequence similarity; putative.
 
     0.464
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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