Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0181Conserved hypothetical protein; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (390 aa)    
Predicted Functional Partners:
sepS
Conserved hypothetical protein; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys); Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
  
 0.987
AF_0180
Predicted coding region AF_0180; Hypothetical protein; identified by GeneMark; putative.
 
     0.927
cysS
cysteinyl-tRNA synthetase (cysS); Similar to GB:D26185 SP:Q06752 GB:L14580 GB:X73989 PID:289284 percent identity: 46.12; identified by sequence similarity; putative.
     
 0.917
AF_0028
Conserved hypothetical protein; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
  
  
 
0.903
AF_0183
Conserved hypothetical protein; Similar to SP:P54432 PID:1303704 GB:AL009126 percent identity: 32.11; identified by sequence similarity; putative.
       0.763
AF_0182
Predicted coding region AF_0182; Hypothetical protein; identified by GeneMark; putative.
       0.762
AF_0218
TRK potassium uptake system protein (trkA-1); Similar to GB:X74307 SP:P39449 PID:414170 percent identity: 30.17; identified by sequence similarity; putative.
   
    0.693
thiI
Conserved hypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.666
AF_0187
Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.
 
     0.642
AF_0009
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase (mtr) {Methanobacterium thermoautotro; Similar to PID:668979 GB:AE000666 percent identity: 42.09; identified by sequence similarity; putative.
  
     0.547
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.