iscU1 protein (Archaeoglobus fulgidus) - STRING interaction network

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iscU1

nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family. (153 aa)

Predicted Functional Partners:

iscS1

0.999

iscS2

0.999

AF_2364

0.882

AF_2365

0.879

AF_0188

0.814

AF_0565

0.801

AF_0184

0.791

AF_0187

0.791

AF_1180

0.785

AF_0632

0.744

Your Current Organism:

Archaeoglobus fulgidus

NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AF_0184	AF_0187	AF_0184	AF_0187	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	0.773
AF_0184	AF_0188	AF_0184	AF_0188	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	0.779
AF_0184	iscS1	AF_0184	AF_0186	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.814
AF_0184	iscU1	AF_0184	AF_0185	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.	0.791
AF_0187	AF_0184	AF_0187	AF_0184	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	0.773
AF_0187	AF_0188	AF_0187	AF_0188	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	0.860
AF_0187	iscS1	AF_0187	AF_0186	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.791
AF_0187	iscU1	AF_0187	AF_0185	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.	0.791
AF_0188	AF_0184	AF_0188	AF_0184	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.	0.779
AF_0188	AF_0187	AF_0188	AF_0187	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.	0.860
AF_0188	iscS1	AF_0188	AF_0186	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.950
AF_0188	iscS2	AF_0188	AF_0564	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.789
AF_0188	iscU1	AF_0188	AF_0185	Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.	nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.	0.814
AF_0565	AF_0632	AF_0565	AF_0632	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	nifU protein (nifU-3); Similar to PID:1653754 percent identity: 47.37; identified by sequence similarity; putative.	0.744
AF_0565	AF_1180	AF_0565	AF_1180	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	Predicted coding region AF_1180; Hypothetical protein; identified by GeneMark; putative.	0.785
AF_0565	AF_2364	AF_0565	AF_2364	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	ABC transporter, ATP-binding protein; Similar to PID:747641 GB:AE000666 percent identity: 52.65; identified by sequence similarity; putative.	0.882
AF_0565	AF_2365	AF_0565	AF_2365	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	Conserved hypothetical protein; Similar to PID:726070 GB:AE000666 percent identity: 46.36; identified by sequence similarity; putative; Belongs to the UPF0051 (ycf24) family.	0.879
AF_0565	iscS1	AF_0565	AF_0186	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.	0.976
AF_0565	iscS2	AF_0565	AF_0564	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.	0.999
AF_0565	iscU1	AF_0565	AF_0185	nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.	nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.	0.801

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