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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0188Conserved hypothetical protein; Similar to GB:L42023 SP:P44841 PID:1005651 PID:1220807 PID:1204969 percent identity: 38.57; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family. (77 aa)    
Predicted Functional Partners:
iscS1
nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 
 0.950
AF_0187
Conserved hypothetical protein; Similar to GB:L77117 PID:1591651 percent identity: 30.69; identified by sequence similarity; putative.
 
   
 0.860
iscU1
nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.
     
 0.814
iscS2
nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
   
 
 0.789
AF_0184
Predicted coding region AF_0184; Hypothetical protein; identified by GeneMark; putative.
       0.779
AF_0183
Conserved hypothetical protein; Similar to SP:P54432 PID:1303704 GB:AL009126 percent identity: 32.11; identified by sequence similarity; putative.
  
  
 0.697
AF_0555
Predicted coding region AF_0555; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.610
AF_1039
Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative.
   
   0.494
AF_0662
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
     
 0.490
AF_0181
Conserved hypothetical protein; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
       0.446
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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