Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0210Predicted coding region AF_0210; Hypothetical protein; identified by GeneMark; putative. (498 aa)    
Predicted Functional Partners:
AF_0209
Conserved hypothetical protein; Similar to SP:P26615 GB:M87049 GB:X65013 PID:148243 percent identity: 42.53; identified by sequence similarity; putative; Belongs to the UbiD family.
       0.773
AF_0211
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58799 PID:1592053 percent identity: 30.77; identified by sequence similarity; putative.
       0.773
guaAA
GMP synthase (guaA-2); Catalyzes the synthesis of GMP from XMP.
       0.624
AF_0282
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60372 PID:1498830 percent identity: 52.63; identified by sequence similarity; putative; Belongs to the UPF0212 family.
       0.601
AF_0208
Signal-transducing histidine kinase; Similar to PID:1001492 PID:1001594 percent identity: 27.88; identified by sequence similarity; putative.
       0.540
secG
Predicted coding region AF_1776; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex (By similarity).
       0.516
AF_2370
Conserved hypothetical protein; Similar to GB:L77117 PID:1499721 percent identity: 29.41; identified by sequence similarity; putative; Belongs to the UPF0148 family.
       0.496
tbp
Transcription initiation factor IID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
     
 0.453
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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