Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0217Na+/H+ antiporter (napA-1); Similar to SP:P26235 PID:148316 percent identity: 28.22; identified by sequence similarity; putative. (377 aa)    
Predicted Functional Partners:
AF_0218
TRK potassium uptake system protein (trkA-1); Similar to GB:X74307 SP:P39449 PID:414170 percent identity: 30.17; identified by sequence similarity; putative.
     
 0.835
leuA
2-isopropylmalate synthase (leuA-2); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
       0.773
AF_1738
Predicted coding region AF_1738; Hypothetical protein; identified by GeneMark; putative.
  
    0.633
argJ
Glutamate N-acetyltransferase (argJ); Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.618
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
       0.537
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
       0.530
AF_0846
Na+/H+ antiporter (nhe2); Similar to PID:1653577 percent identity: 33.13; identified by sequence similarity; putative.
   
 
 0.492
AF_1244
Predicted coding region AF_1244; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.438
AF_1245
Na+/H+ antiporter (napA-2); Similar to SP:P26235 PID:148316 percent identity: 28.41; identified by sequence similarity; putative.
 
  
 0.428
AF_1724
Dinitrogenase reductase activating glycohydrolase (draG); Similar to GB:L77117 PID:1591815 percent identity: 37.92; identified by sequence similarity; putative; Belongs to the ADP-ribosylglycohydrolase family.
 
  
 0.424
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.