STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pycABiotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (506 aa)    
Predicted Functional Partners:
AF_0074
Biotin operon repressor/biotin--[acetyl CoA carboxylase] ligase (birA); Similar to SP:P42975 PID:1146239 PID:755608 PID:773349 GB:AL009126 percent identity: 36.59; identified by sequence similarity; putative.
 0.997
AF_1252
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:L77117 PID:1591862 percent identity: 63.26; identified by sequence similarity; putative.
 
  
 0.990
AF_2217
methylmalonyl-CoA decarboxylase, subunit alpha (mmdA); Similar to GB:L22208 GB:Z24754 PID:415593 PID:415915 percent identity: 62.52; identified by sequence similarity; putative.
  
 
 0.966
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 0.963
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
  
 0.952
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
    
 0.951
AF_2085
Oxaloacetate decarboxylase, biotin carboxyl carrier subunit, putative; Similar to GB:M80523 SP:P29337 PID:153584 percent identity: 38.74; identified by sequence similarity; putative.
  
 
 0.944
AF_2216
methylmalonyl-CoA decarboxylase, biotin carboxyl carrier subunit (mmdC); Similar to GB:L22208 GB:Z24754 PID:415596 PID:415918 percent identity: 36.22; identified by sequence similarity; putative.
  
 
 0.944
korB
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); Similar to GB:L77117 PID:1591241 percent identity: 51.38; identified by sequence similarity; putative.
    
 0.943
AF_1699
Pyruvate ferredoxin oxidoreductase, subunit gamma (porG); Similar to PID:1197358 percent identity: 50.84; identified by sequence similarity; putative.
    
 0.943
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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