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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0231Glutamine ABC transporter, periplasmic glutamine-binding protein (glnH); Similar to SP:P10344 PID:41569 GB:U00096 PID:1651365 PID:1651371 percent identity: 38.01; identified by sequence similarity; putative. (264 aa)    
Predicted Functional Partners:
AF_0232
Glutamine ABC transporter, permease protein (glnP); Similar to SP:P10345 PID:41572 GB:U00096 PID:1651370 PID:1787030 percent identity: 39.25; identified by sequence similarity; putative.
 
 0.997
AF_0680
Glutamine ABC transporter, ATP-binding protein (glnQ); Similar to GB:M61017 SP:P27675 PID:142988 percent identity: 63.83; identified by sequence similarity; putative.
 
 0.944
AF_1039
Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative.
   
   0.640
aroA
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
  
  
 0.575
AF_0227
Chorismate mutase/prephenate dehydratase (pheA); Similar to GB:L42023 SP:P43900 PID:1006481 PID:1221267 PID:1205390 percent identity: 32.15; identified by sequence similarity; putative.
     
 0.551
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.534
argG
Argininosuccinate synthetase (argG); Similar to GB:L77117 SP:Q60174 PID:1591132 percent identity: 62.02; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.532
aroD
3-dehydroquinate dehydratase (aroD); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
     
 0.522
argH
Argininosuccinate lyase (argH); Similar to SP:Q58201 PID:1591489 GB:L77117 SP:Q58201 PID:1591489 percent identity: 42.23; identified by sequence similarity; putative.
  
  
 0.519
aroB
Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family.
       0.469
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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